ncRNA name | hsa-miR-613 |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines SO-RB50, Y79 and WERI-RB1; RPE cell line ARPE-19; RB samples, normal retinas |
Methods | transfection, qPCR, MTT assay, colony formation assay, BrdU staining, transwell assay, flow cytometry, Western blot, xenograft |
Expression pattern | down-regulated |
Functional description | miR-613 functions as a tumor suppressor in retinoblastoma through downregulating E2F5, supporting the targeting of the novel miR-613/E2F5 axis as a potentially effective therapeutic approach for retinoblastoma. |
PubMed ID | 28351331 |
Year | 2017 |
Title | MiR-613 suppresses retinoblastoma cell proliferation, invasion, and tumor formation by targeting E2F5. |
Drug-related ncRNA | NO |
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